A Secondary hyperparathyroidism revealed by a mandibular radiolucency: case report
Modern surgical endodontics: Acomprehensive clinical approach
13 mars 2025Rotational Crestal Flap Associated with PRF: A novel Technique for Oroantral communication closure
28 mai 2025Auteurs: Mohamed Beh, Ghada Bouslama, Wahbi Ben Salha, Lamia Oualha, Eya Moussaoui, Souha Ben youssef
Abstract
Brown tumors are rare, non-neoplastic osteolytic lesions resulting from hyperparathyroidism (HPT), most often seen in long bones but occasionally affecting the jaw. This report presents a 28-year-old male with chronic renal failure on dialysis, referred for dental evaluation prior to kidney transplantation. A panoramic radiograph revealed bilateral radiolucent mandibular lesions. Clinical and vitality tests excluded periapical pathology. Biochemical tests showed markedly elevated parathyroid hormone (PTH = 3919 pg/ml), consistent with secondary HPT. Cervical ultrasound identified a parathyroid adenoma. The patient underwent parathyroidectomy without direct surgical treatment of the jaw lesions. One year postoperatively, radiographs showed spontaneous reossification and lesion regression. Brown tumors typically regress following correction of HPT, though surgical excision may be required in persistent cases. Early diagnosis can prevent unnecessary dental procedures. This case underscores the importance of considering secondary HPT in jaw radiolucencies, especially in patients with renal disease.
Keywords: brown tumor, jaw, hyperparathyroidism, parathormone, bone remodeling, enucleation
